Genetic lesions within the 3a gene of SARS-CoV

作者：Tan Timothy H P^*; Barkham Timothy; Fielding Burtram C; Chou Chih Fong; Shen Shuo; Lim Seng Gee; Hong Wanjin; Tan Yee Joo

来源：Virology Journal, 2005, 2: 51.

DOI：10.1186/1743-422X-2-51

A series of frameshift mutations within the 3a gene has been observed in culture-derived severe acute respiratory syndrome coronavirus (SARS-CoV). We report here that viral RNA from clinical samples obtained from SARS-CoV infected patients also contains a heterogeneous population of wild-type and mutant 3a transcripts.

• 出版日期2005