Association of antimullerian hormone levels with menstrual-cycle type and dysmenorrhea in young asymptomatic women

作者：Konishi Shoko^*; Nishihama Yukiko; Iida Ayaka; Yoshinaga Jun; Imai Hideki

来源：Fertility and Sterility, 2014, 102(5): 1439-1443.

DOI：10.1016/j.fertnstert.2014.07.1255

• Antimullerian hormone
• menstrual-cycle regularity
• menstrual pain
• young women

Objective: To examine the association between antimullerian hormone (AMH) levels and menstrual-cycle and lifestyle characteristics among young Japanese women. %26lt;br%26gt;Design: Cross-sectional study. %26lt;br%26gt;Setting: University. %26lt;br%26gt;Patient(s): Female students aged 20-22 years (n = 65) who had never used oral contraceptives. %26lt;br%26gt;Intervention(s): Participants completed a questionnaire on reproductive and lifestyle characteristics, and kept a menstrual-cycle diary for 5 consecutive months. Serum AMH was measured once during the study period. %26lt;br%26gt;Main Outcome Measure(s): Serum AMH concentration. %26lt;br%26gt;Result(s): Compared with women with very mild menstrual pain, serum AMH concentration was 49.6% (95% CI 6.5%-72.8%) lower among women with severe menstrual pain. Higher AMH concentration was associated with irregular menstrual cycles. Even after adjusting for menstrual-cycle regularity and its interaction, more-severe menstrual pain was associated with significantly lower AMH concentration. %26lt;br%26gt;Conclusion(s): Circulating AMH concentration was significantly lower among young Japanese women who had more-severe menstrual pain. Underlying physiological mechanisms need to be addressed in future studies.

• 出版日期2014-11