Sterigmatocystins from the deep-sea-derived fungus Aspergillus versicolor

作者：Cai Shengxin; Zhu Tianjiao; Du Lin; Zhao Boyu; Li Dehai^*; Gu Qianqun

来源：Journal of Antibiotics, 2011, 64(2): 193-196.

DOI：10.1038/ja.2010.154

• Aspergillus versicolor
• deep-sea
• fungus
• sterigmatocystin

Three new sterigmatocystin derivatives, oxisterigmatocystin A (1), oxisterigmatocystin B (2) and oxisterigmatocystin C (3), together with one known compound, 5-methoxysterigmatocystin (4), were isolated from the deep-sea-derived fungus Aspergillus versicolor. The structures of the new compounds were elucidated by spectroscopic methods. The cytotoxicities of compounds 1-4 were evaluated against the A-549 and HL-60 cell lines. Compound 4 exhibited moderate cytotoxicities against the A-549 and HL-60 cell lines with IC(50) value of 3.86 and 5.32 mu m, respectively. The Journal of Antibiotics (2011) 64, 193-196; doi:10.1038/ja.2010.154; published online 1 December 2010

• 出版日期2011-2
• 单位中国海洋大学