摘要

Actinomycin D(AMD) is well known for its specific inhibition of DNA transcription, and has been used clinically as an antitumor drug for the treatment of some highly malignant tumors. Based on the former research, two [D-Phe 2] 2AMD analogs with L-MeVal(the fifth amino acid residue in the cyclic ...

  • 出版日期2004
  • 单位功能有机分子化学国家重点实验室; 生命科学学院; 兰州大学