Adiposity rather than BMI determines metabolic risk

作者:De Lorenzo Antonino*; Bianchi Alessia; Maroni Pasquale; Iannarelli Annarita; Di Daniele Nicola; Iacopino Leonardo; Di Renzo Laura
来源:International Journal of Cardiology, 2013, 166(1): 111-117.
DOI:10.1016/j.ijcard.2011.10.006

摘要

Background and aim: There is increasing evidence suggesting that WHO body mass index (BMI) cut-off values are outdated and should not be applied to different population. To overcome misclassifications, direct measurements of percentage body fat (PBF) would be a better tool for preobesity and obesity diagnosis. The aim of this study was to analyze the body composition in a adult population in Centre-South of Italy, by age and gender, and to verify the accordance between BMI and PBF cut-off points for health status classification. %26lt;br%26gt;Methods: The total subject pool cover a total of 4408 participants adults. A completed screening of anthropometry and body composition by Dual X-ray Absorptiometry, (DXA) was assessed on 3.258 subjects. %26lt;br%26gt;Results: Distributions and quantitative reliable estimates of PBF, total body fat and lean, according to gender and age are provided. The prevalence of %26quot;at risk%26quot; subjects (preobese and obese) was 69% and 85%, for men and women respectively, according to PBF cut-off points. The agreement of BMI and PBF categories resulted low for the total and male population, even scarce for female population (all P %26lt;= 0.001). The false negative classification of BMI was stronger for women than men and for younger than older subjects. %26lt;br%26gt;Conclusions: Screening for adiposity in subjects with a normal BMI could better identify those at higher risk for cardiometabolic disturbances and cardiovascular mortality. The herein used cut-offs points of PBF, by age and gender, may provide a useful reference in clinical settings and public health services, in particular for the Italian Caucasian population.

  • 出版日期2013-6-5