Direct C-2 Arylation of 7-Azaindoles: Chemoselective Access to Multiarylated Derivatives

作者：Kannaboina Prakash; Anilkumar K; Aravinda S; Vishwakarma Ram A; Das Parthasarathi^*

来源：Organic Letters, 2013, 15(22): 5718-5721.

DOI：10.1021/ol4027478

Pd-catalyzed direct C-H arylation of N-methyl-7-azaindole at the C-2 position by diverse arylboronic acids was achieved at room temperature. The method is general and was applied in chemoselective synthesis of multiarylated 7-azaindole derivatives bearing three different aryl groups at the 2, 3, and 5 positions.

• 出版日期2013-11-15