A Noisy Tug of War: The Battle between Transcript Production and Degradation in the Liver

作者：Lam Alec; Deans Tara L^*

来源：Developmental Cell, 2015, 33(1): 3-4.

DOI：10.1016/j.devcel.2015.03.019

Genetically identical cells in culture often exhibit significant variations, or noise, in gene expression, largely due to transcriptional bursting. Halpern et al. (2015) have developed methods to study gene bursting in tissues to find that this transcriptional bursting also occurs in the mammalian liver and may contribute to functional plasticity in hepatocytes.

• 出版日期2015-4-6