Apomorphine therapy in Parkinson's disease: a review

作者：Haq Ihtsham Ul^*; Lewitt Peter A; Fernandez Hubert H

来源：Expert Opinion on Pharmacotherapy, 2007, 8(16): 2799-2809.

DOI：10.1517/14656566.8.16.2799

• apomorphine
• motor fluctuation
• Parkinson's disease

Motor fluctuations are common and distressing for patients with advanced Parkinson's disease. Subcutaneous apornorphine injections can be an extremely valuable adjunctive therapy. In this review, the authors discuss the history, pharmacology, efficacy, safety and proper administration of apomorphine for treating 'off' states in Parkinson's disease, with a focus on intermittent subcutaneous administration.

• 出版日期2007-11