A "turn-on'' silver nanocluster based fluorescent sensor for folate receptor detection and cancer cell imaging under visual analysis

作者:Jiang, Hong; Xu, Gang; Sun, Yimin; Zheng, Weiwei; Zhu, Xiangxiang; Wang, Baojuan; Zhang, Xiaojun; Wang, Guangfeng*
来源:Chemical communications, 2015, 51(59): 11810-11813.
DOI:10.1039/c5cc02061a

摘要

A novel terminal protection based label-free and "turn-on'' fluorescent sensor for detection of folate receptors (FRs) and HeLa cells is developed by fluorescence resonance energy transfer (FRET) between single-walled carbon nanotubes (SWCNTs) and silver nanoclusters (AgNCs). Multilevel visual analysis (m(2)VA) was firstly proposed and applied in optimizing the experimental parameters.