A facile and expeditious microwave-assisted synthesis of 4-aryl-2-ferrocenyl-quinoline derivatives via multi-component reaction

作者:Tu Shu Jiang*; Yan Shu; Cao Xu Dong; Wu Shan Shan; Zhang Xiao Hong; Hao Wen Juan; Han Zheng Guo; Shi Feng
来源:Journal of Organometallic Chemistry, 2009, 694(1): 91-96.
DOI:10.1016/j.jorganchem.2008.10.007

摘要

An efficient and rapid route for the synthesis of 4-aryl-2-ferrocenyl-quinoline derivatives through microwave-assisted multi-component reaction of acetylferrocene with aromatic aldehyde and dimedone in the presence of ammonium acetate using DMF as reaction media at 100 degrees C is described. This novel procedure lends itself well to combinatorial methods, providing the target heteropolymetallic compounds in excellent yield without further purification.