Additive Interaction of Oral Health Disorders on Risk of Hypertension in a Japanese Urban Population: The Suita Study

作者：Iwashima Yoshio^*; Kokubo Yoshihiro; Ono Takahiro; Yoshimuta Yoko; Kida Momoyo; Kosaka Takayuki; Maeda Yoshinobu; Kawano Yuhei; Miyamoto Yoshihiro

来源：American Journal of Hypertension, 2014, 27(5): 710-719.

DOI：10.1093/ajh/hpt227

• blood pressure
• hypertension
• life style
• oral health disorder
• risk factor

This study assessed the relationship between different oral health markersuperiodontitis, gingival bleeding, tooth number, and occlusal statusuand hypertension in a Japanese urban population.
A total of 1,643 participants with no prior cardiovascular disease (mean age 66.6 years; 43.4% women) underwent comprehensive health checkups, including a lifestyle questionnaire and dental examination in the Suita Study.
In the multivariable-adjusted logistic model, none of the individual oral health markers, namely severe periodontitis, gingival bleeding, lowest quartile of tooth number, and malocclusion, were significantly associated with increased odds of hypertension. The additive effects of oral health markers on hypertension were examined and showed that, compared with subjects with no component of the oral health markers, the multivariale-adjusted odds ratio of hypertension in those with 3 components was 1.82 (95% confidence interval (CI) 1.232.72; P 0.003). In the subpopulation without antihypertensive medication (n 1,148; 59.8% women), a significant graded relationship between multivariable-adjusted systolic blood pressure and the number of components was found (P-trend 0.03), and, compared with subjects with no component of the oral health markers, having 3 components was related to a higher systolic blood pressure ( 5.41; 95% CI 1.169.66; P 0.01).
There is an additive relationship between oral health disorders and risk of hypertension. Our results suggest that the existence of moderate or severe oral health disordersuthat is, several concomitant oral health disordersuis associated with risk of hypertension.

• 出版日期2014-5