Double uterus with obstructed hemivagina and ipsilateral renal agenesis: pelvic anatomic variants in 87 cases

作者：Fedele L^*; Motta F; Frontino G; Restelli E; Bianchi S

来源：Human Reproduction, 2013, 28(6): 1580-1583.

DOI：10.1093/humrep/det081

• double uterus
• Herlyn-Werner-Wunderlich syndrome
• obstructed hemivagina
• cervical agenesis
• didelphys

What are the anatomic variants (and their frequencies) of double uterus, obstructed hemivagina and ipsilateral renal agenesis? %26lt;br%26gt;Most cases examined (72.4) were of the classic anatomic variant of the Herlyn-Werner-Wunderlich syndrome (with didelphys uterus, obstructed hemivagina and ipsilateral renal agenesis) but the 27.6 of cases are of a rare variant of the syndrome (with uterus septum or cervical agenesis), showing relevant clinical and surgical implications. %26lt;br%26gt;The extreme variability of anatomic structures involved in this syndrome (both uterus, cervico-vaginal and renal anomalies) is well known, even if a complete and uniform analysis of all its heterogeneous presentations in a large series is lacking. %26lt;br%26gt;This is a retrospective study with 87 patients referred to our third level referral center between 1981 and 2011. %26lt;br%26gt;We analyzed the laparoscopic and chart records of 87 women, who referred to our institute with double uterus, unilateral cervico-vaginal obstruction and ipsilateral renal anomalies. %26lt;br%26gt;Sixty-three of 87 patients had the more classic variant of didelphys uterus with obstructed hemivagina; 10/87 patients had septate bicollis uterus with obstructed hemivagina; 9/87 patients had bicornuate bicollis uterus with obstructed hemivagina; 4/87 patients had didelphys uterus with unilateral cervical atresia; 1/87 patients had bicornuate uterus with one septate cervix and unilateral obstructed hemivagina. %26lt;br%26gt;This is a retrospective study with a long enrolling period (30 years). %26lt;br%26gt;New insights in the anatomic variants of this rare syndrome with their relevant surgical implications. %26lt;br%26gt;No specific funding was obtained for this study. None of the authors have any competing interests to declare. %26lt;br%26gt;N/A.

• 出版日期2013-6