Herpes zoster oticus: A clinical model for a transynaptic, reflex pathways, viral transmission hypotheses

作者：Alicandri Ciufelli Matteo; Aggazzotti Cavazza Elisa^*; Genovese Elisabetta; Monzani Daniele; Presutti Livio

来源：Neuroscience Research, 2012, 74(1): 7-9.

DOI：10.1016/j.neures.2012.06.001

• Herpes zoster oticus
• Ramsay-Hunt
• Intersynaptic transmission
• Multiple cranial nerve palsies
• Brainstem reflex pathways
• Herpes zoster transmission
• Varicella zoster
• Anterograde pathway

Reactivation of the varicella-zoster virus (VZV) along the sensory nerves innervating the ear, including the geniculate ganglion, is responsible for herpes zoster oticus (HZO). In some cases, HZO is associated with polyneuropathy of the cranial nerves, although the mechanism of this involvement is not known. To explain this phenomenon and based on some clinical considerations, the present authors hypothesize an intersynaptic spread of VZV along the reflex pathways of the brainstem.

• 出版日期2012-9