A novel approach to identify the rate constants of ion channel of four-state-loop via partially observable information

作者：Xiang Xuyan^*

来源：International Conference on Advanced in Control Engineering and Information Science (CEIS), 2011-08-18 to 2011-08-19.

DOI：10.1016/j.proeng.2011.08.920

• Ion channel
• four-state-loop
• rate constants
• open litetime
• shut lifetime

Among the equations between rate constants and the derivatives, the novel equations between rate constants and the moments of open and shut lifetime distribution for a given state set of Markov Chain are applied to identify the rate constants of ion channels. For gating scheme of ion channels of four-state-loop, it is derived by the underlying information that rate constants can be identified by their open lifetime and shut lifetime distributions at any two states.

• 出版日期2011
• 单位湖南大学