Preparation of C-2-Symmetric Allenes by Palladium-Catalyzed Double-Nucleophilic Substitution on 3-Bromopenta-2,4-dienyl Acetate

作者:Ogasawara Masamichi*; Suzuki Mayuka; Takahashi Tamotsu
来源:Journal of Organic Chemistry, 2012, 77(12): 5406-5410.
DOI:10.1021/jo300511e

摘要

Easily accessible 3-bromopenta-2,4-dienyl acetate was applied to the palladium-catalyzed reaction with soft nucleophiles. The reaction proceeded through the stepwise 2-fold nucleophilic substitution via formal S(N)2%26apos; and S(N)2 processes giving the various doubly functionalized C-2-symmetric allenes in good yields.

  • 出版日期2012-6-15