Online Kt/V Monitoring in Haemodialysis by UV Absorbance: Variations during Intra-Dialytic Meals

作者：Mueller Deile Janina; Lichtinghagen Ralf; Haller Hermann; Schmitt Roland^*

来源：Blood Purification, 2014, 37(2): 113-118.

DOI：10.1159/000358212

• Kt/V
• Haemodialysis
• UV absorbance
• Intra-dialytic meals

Background/Aims: The aim of this study was to analyse if intra-dialytic food intake may lead to changes in online Kt/V. Methods: Forty patients were analysed using haemodialysis machines with integrated online Kt/V monitoring based on UV absorbance or ionic dialysance. Kt/V was monitored before, during and after food intake. Samples of dialysate were analysed for urea, uric acid, creatinine and glucose levels. Results: Food intake was associated with a significant decrease in relative Kt/V when determined by UV absorbance. The drop in Kt/V was independent of changes in blood pressure or body posture. No significant changes in online Kt/V were found using the ionic dialysance method. Dialysate samples showed a continuous clearance of urea, uric acid and creatinine during meals but a rapid increase in glucose. Conclusion: Our data suggest that the short meal-associated decrease in online Kt/V as measured by UV absorbance does not represent a true decline in Kt/V but might reflect an intermittent increase in UV-absorbing dialysed solutes.

• 出版日期2014