Assembly, Fluorescence Properties and Antitumor Activity of Novel Silver(I) Cyanide Supramolecular Coordination Polymer Based on Trans-1,2-bis(4-pyridyl)ethene and Me3SnCl

作者：Etaiw Safaa El din H^*; El din Ahmed S Badr

来源：Journal of Inorganic and Organometallic Polymers and Materials, 2012, 22(2): 478-491.

DOI：10.1007/s10904-011-9602-7

• Supramolecular
• Silver(I) cyanide
• Trans-1,2-bis(4-pyridyl)ethene
• Luminescence trimethyltin group
• Anti-tumor activity

A bimetallic supramolecular coordination polymer; {[(Me3Sn)(8)Ag-4(OH)(4)(CN)(8)(tbpe)](tbpe)} (n) , 1, was obtained by the reaction in situ of K-2[Ag(CN)(2)] with Me3SnCl and trans-1,2-bis(4-pyridyl)ethene (tbpe) in a H2O/MeCN/NH3 solvent. The structure of 1 consists of discrete puckered tetranuclear chains comprising {[(Me3Sn)(4)Ag-2(OH)(2)(CN)(4)](2)(tbpe)} in addition to one template free tbpe ligand. In these chains, the bridging hydroxyl group and the bipodal tbpe ligand are used to give two novel spacers based on the organometallic Me3Sn unit; i.e., a longer spacer [-CN-(Me-3)Sn-O(H)-(Me-3)Sn-L-(Me-3)Sn-O(H)-(Me-3)Sn-NC-] with a separation distance of 31.29 , and a relatively shorter spacer [-CN-(Me-3)Sn-O(H)-(Me-3)Sn-NC-] with a separation distance of 14.431 . Supramolecular interactions such as hydrogen bonding, pi-pi stacking, cation center dot center dot center dot pi interactions, play a prominent role in the assembly of this compound. The structure of the SCP was also investigated by FTIR and electronic absorption spectra and thermal analysis and the data are compared to the prototype compounds. The SCP 1 exhibits strong fluorescence in acetonitrile and shows specific in vitro antitumor activity against human breast cancer cell line, MCF7.

• 出版日期2012-3