A one-pot multicomponent synthesis of polysubstituted thiophenes via the reactions of an isocyanide, alpha-haloketones, and beta-ketodithioesters in water

作者：Moghaddam Firouz MatIoubi^*; Khodabakhshi Mohammad Reza; Latifkar Arash

来源：Tetrahedron Letters, 2014, 55(6): 1251-1254.

DOI：10.1016/j.tetlet.2014.01.014

• Polysubstituted thiophene
• Isocyanide
• Multicomponent reactions

An efficient synthesis of polysubstituted thiophene derivatives is achieved via the multicomponent reaction of beta-ketodithioesters, alpha-haloketones, and cyclohexylisocyanide in aqueous medium.

• 出版日期2014-2-5