Hysteroscopic findings in women with two and with more than two first-trimester miscarriages are not significantly different

作者：Bohlmann Michael K^*; von Wolff Michael; Luedders Doerte W; Beuter Winkler Petra; Diedrich Klaus; Hornemann Amadeus; Strowitzki Thomas

来源：Reproductive BioMedicine Online, 2010, 21(2): 230-236.

DOI：10.1016/j.rbmo.2010.04.016

• acquired
• congenital
• hysteroscopy
• recurrent miscarriages
• uterine anomaly

The purpose of this study was to analyse hysteroscopic results in patients with recurrent miscarriages and to compare the frequency of uterine anomalies in women with a history of exactly two and with more than two consecutive miscarriages. A retrospective analysis of 206 patients undergoing hysteroscopy for repeated early pregnancy losses was performed at two university centres. Late miscarriages were excluded, terminations of pregnancy were not counted. Eighty-seven patients had suffered from exactly two early miscarriages and 119 from more than two. Both groups were comparable with respect to age at admission (32.95 +/- 4.46 versus 34.06 +/- 5.02 years) and at first miscarriage (30.43 +/- 4.24 versus 29.08 +/- 5.38 years). The prevalence of acquired (adhesions, polyps, fibroids) and congenital uterine anomalies (septate or bicornuate uterus, etc.) did not differ significantly (acquired: 28.7 versus 27.7%; congenital: 9.2 versus 16.8%). The rates of uterine anomalies did not differ significantly overall (36.8 versus 42.9%). In conclusion, uterine anomalies are frequently found in patients with two and with more than two early miscarriages. Due to the high rate of anomalies, their risk for adverse pregnancy outcome and a possible therapeutic approach, hysteroscopy might be a diagnostic option even after two early miscarriages.

• 出版日期2010-8