Understanding the nanoindentation mechanisms of a microsphere for biomedical applications

作者:Chen Jinju*
来源:Journal of Physics D: Applied Physics , 2013, 46(49): 495303.
DOI:10.1088/0022-3727/46/49/495303

摘要

Nanoindentation techniques have proven effective to characterize nanomaterials and soft biomaterials. Using microfabricated wells to hold microspheres will enable automated indentation of microspheres. However, the existing contact mechanics based models such as the Hertz model and other modified models (e. g. thin layer models) only deal with indenting the specimen placed on a flat surface (i.e. the bottom surface is constrained vertically) without lateral constraint. Therefore, new mathematical models have been developed in this study to investigate the nanoindentation responses for a microsphere sitting in a well. Finite element simulation was employed to determine the empirical correction parameter in the mathematical model to account for the constraint imposed by the well. Utilization of this new model can also enrich the experimental contact mechanics.

  • 出版日期2013-12-11