Acute disseminated encephalomyelitis following inactivated influenza vaccination in the Brazilian Amazon: a case report

作者:de Andrade Solange Dourado*; Filha Santarem Andrade Maria Graciede; Santos Pablo Jose; Galvao Maria de Lourdes; de Barros Mariana Martins; Ramasawmy Rajendranath; Safe Izabella Picinin; Monteiro Wuelton Marcelo; Sabido Meritxell; Costa Alecrim Maria das Gracas
来源:Revista da Sociedade Brasileira de Medicina Tropical, 2015, 48(4): 498-500.
DOI:10.1590/0037-8682-0314-2014

摘要

Here, we describe a case of acute disseminated encephalomyelitis (ADEM) that occurred during a plausible risk interval following inactivated influenza vaccination in a previously healthy 27-year-old man from Manaus, Brazil. He was treated with intravenous methylprednisolone and immunoglobulin. One-month follow-up revealed resolution of the brain lesions, but not of the spinal cord lesions. No recurrence or progression of the main neurological symptoms was observed. After two years of monitoring, the patient continues to experience weak lower limbs and urinary retention. Thus, we recommend that ADEM should be considered in a patient presenting with neurological symptoms after influenza vaccination.

  • 出版日期2015-8