A new method of synthesis of fluorescently labelled oligonucleotides and their application in DNA sequencing

作者:Markiewicz WT*; Groger G; Rosch R; Zebrowska A; Markiewicz M; Klotz M; Hinz M; Godzina P; Seliger H
来源:Nucleic Acids Research, 1997, 25(18): 3672-3680.
DOI:10.1093/nar/25.18.3672

摘要

A new approach to the chemical synthesis of oligodeoxynucleotides bearing reporter functional groups at base residues of 3'-end nucleosides is reported, Applications of the 3'-end fluorescently labelled primers for automated DNA sequencing are shown.

  • 出版日期1997-9-15

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