An Efficient Method for the N-Bromosuccinimide Catalyzed Synthesis of Indolyl-Nitroalkanes

作者:Kuo Chun Wei; Wang Chun Chao; Fang Hu Lin; Raju B Rama; Kavala Veerababurao; Habib Pateliya Mujjamil; Yao Ching Fa*
来源:Molecules, 2009, 14(10): 3952-3963.
DOI:10.3390/molecules14103952

摘要

An efficient and practical method for the synthesis of indolyl-nitroalkane derivatives catalyzed by N-bromosuccinimide is described. The generality of this method was demonstrated by synthesizing an array of diverse 3-substituted indole derivatives by the reaction of different beta-nitrostyrenes with various substituted indoles. Simple reaction conditions accompanied by good yields of indolyl-nitroalkanes are the merits of this methodology.

  • 出版日期2009-10