摘要
An efficient and convenient method for the preparation of 3-carbonitrile pyridin-2(1H)-one derivative by the one-pot reaction of aromatic aldehydes, acetones and 2-cyanoacetamide in the presence of sodium hydroxide under solvent-free condition was reported. This method has the advantages of excellent yields, mild reaction conditions, easy work-up, and environmentally friendly procedure.
- 出版日期2012-2
- 单位中国矿业大学(北京); 江苏师范大学