An efficient ultrasonic-assisted synthesis of imidazolium and pyridinium salts based on the Zincke reaction

作者：Zhao Sanhu^*; Xu Xiaoming; Zheng Lu; Liu Hai

来源：Ultrasonics Sonochemistry, 2010, 17(4): 685-689.

DOI：10.1016/j.ultsonch.2009.12.019

• Zincke reaction
• Primary amine
• Ultrasound
• Pyridinium salts
• Imidazolium salts

A mild and efficient method has been developed using ultrasound irradiation for the synthesis of imidazolium and pyridinium salts based on the Zincke reaction Tertiary nitrogen nucleophiles such as pyridines and imidazoles can be alkylated with primary amine by simply using their ammonium form Zincke salts In almost all cases, a clear yield increase results and a dramatic reduction of the reaction time accompanied by an improved quality of the products occurs.

• 出版日期2010-4
• 单位忻州师范学院