A new pregnane steroid from cultures of Aspergillus versicolor

作者：Ding, Jian-Hai^*; Ding, Zhang-Gui; Zhao, Jiang-Yuan; Li, Ming-Gang; Hu, Dong-Bao^*; Jiang, Xian-Jun; Zhou, Dong-Sheng; Wang, Fei^*; Wen, Meng-Liang^*

来源：Natural Product Research, 2019, 33(13): 1885-1890.

DOI：10.1080/14786419.2018.1478828

• Aspergillus versicolor
• secondary metabolite
• absolution configuration
• electronic circular dichroism

A new pregnane steroid, named aspergillon A (1), together with two known compounds, (22E,24R)-ergosta-5,7,22-trien-3 beta-ol (2) and (22E, 24R)-ergosta-4,6,8(14),22-tetraen-3-one (3) were isolated from cultures of the tin mine tailings-associated fungus Aspergillus versicolor. The new structure and absolute configuration were determined with the help of extensive spectroscopic analyses and quantum chemical calculations of the electronic circular dichroism (ECD) spectra.
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• 出版日期2019-7-3
• 单位宁夏师范学院; 云南大学; 玉溪师范学院