Arsenic Exposure and Oral Cavity Lesions in Bangladesh

作者：Syed Emdadul H; Melkonian Stephanie; Poudel Krishna C; Yasuoka Junko; Otsuka Keiko; Ahmed Alauddin; Islam Tariqul; Parvez Faruque; Slavkovich Vesna; Graziano Joseph H; Ahsan Habibul; Jimba Masamine^*

来源：Journal of Occupational and Environmental Medicine, 2013, 55(1): 71-78.

DOI：10.1097/JOM.0b013e31826bb686

Objective: To evaluate the relationship between arsenic exposure and oral cavity lesions among an arsenic-exposed population in Bangladesh. Methods: We carried out an analysis utilizing the baseline data of the Health Effects of Arsenic Exposure Longitudinal Study, which is an ongoing population-based cohort study to investigate health outcomes associated with arsenic exposure via drinking water in Araihazar, Bangladesh. We used multinomial regression models to estimate the risk of oral cavity lesions. Results: Participants with high urinary arsenic levels (286.1 to 5000.0 mu g/g) were more likely to develop arsenical lesions of the gums (multinomial odds ratio = 2.90; 95% confidence interval, 1.11 to 7.54), and tongue (multinomial odds ratio = 2.79; 95% confidence interval, 1.51 to 5.15), Compared with those with urinary arsenic levels of 7.0 to 134.0 mu g/g. Conclusions: Higher level of arsenic exposure was positively associated with increased arsenical lesions of the gums and tongue.

• 出版日期2013-1