Phosphatase Activity Controls the Ups and Downs of Cerebellar Learning

作者:Carey Megan R*; Regehr Wade G
来源:Neuron, 2010, 67(4): 525-526.
DOI:10.1016/j.neuron.2010.08.015

摘要

Investigations of the cellular substrate for cerebellar learning have focused largely on a single form of plasticity, kinase-dependent long-term depression (LTD). In this issue of Neuron, Schonewille et al. provide evidence that calcineurin, a protein phosphatase required for long-term potentiation (LTP) and other cellular processes, may be just as important.

  • 出版日期2010-8-26