A Novel Young's Modulus Reconstruction Method Based on a Modified Plane-Strain Model

作者：Pan, Xiaochang; Huang, Jianyong^*; Feng, Naizhang; Chen, Siping^*

来源：Journal of Medical Imaging and Health Informatics, 2018, 8(5): 915-924.

DOI：10.1166/jmihi.2018.2407

• Breast Elastography
• Inverse Problem
• Image Reconstruction
• Biomechanical Modeling
• Finite Element Method

Quantification of Young's modulus (YM) in breast tissues has significant pathological and clinic implications because changes in the local YM within tissue have been correlated with their pathological state. The YM reconstruction technique based on ultrasound elastography provides a feasible way for quantitatively evaluating spatial variation in YM within the tissues. Most of the existing YM reconstruction methods, however, only treat actual tissue deformation caused by transducer compression as a classical plane strain/stress model in the quasi-static ultrasound elastography. To better capture 3D tissue deformation information, this paper proposed a modified plane-strain model by introducing a group of surface forces acting on tissues imaged by a 2D ultrasonic probe to describe mechanical interactions of imaging tissue with the surrounding tissues. Accordingly, a set of novel algorithms was developed to recover YM fields in a manner of convex optimization. Both simulations and phantom experiments indicated that the set of algorithms were not only simple and easy to use but also able to remarkably enhance the robustness and accuracy of YM reconstruction for breast lesions or inclusions, which was crucial to early diagnosis of breast tumors in the clinic.

• 出版日期2018-6
• 单位北京大学; 深圳大学