Arthritis: an unusual and anticipatory presentation of pediatric acute lymphoblastic leukemia: case report

作者:Duarte Salazar Carolina; Guadalupe Santillan Chapa Concepcion; Daniel Gonzalez Rosado Garly; Marin Arriaga Norma; Eugenio Vazquez Meraz Jose
来源:Cirugia y Cirujanos, 2012, 80(5): 425-428.

摘要

Background: Acute lymphoblastic leukemia (ALL) shows osteoarticular manifestations. However, it is rare that it shows symptoms of juvenile idiopathic arthritis (JIA).
Clinical case: We present the case of a child with ALL initially misdiagnosed as JIA. The child had persistent articular pain and swelling despite treatment. Six months later, comprehensive blood count revealed leukopenia and neutropenia with lymphocytosis. Bone marrow aspirate confirmed pre-B ALL with hypodiploidy.
Conclusion: This case initially showed typical signs of arthritis. Diagnosis of ALL was ruled out because of the absence of clinical features and hematologic alterations characterizing this hematological neoplasm.

  • 出版日期2012-10