Dietary Alpha-Tocopherol Affects Tissue Vitamin E and Malondialdehyde Levels but Does not Change Antioxidant Enzymes and Fatty Acid Composition in Farmed Atlantic Salmon (Salmo solar L.)

作者：Faizan Mohammad; Stubhaug Ingunn; Menoyo David; Esatbeyoglu Tuba; Wagner Anika Eva; Struksnaes Gunvor; Koppe Wolfgang; Rimbach Gerald^*

来源：International Journal for Vitamin and Nutrition Research, 2013, 83(4): 238-245.

DOI：10.1024/0300-9831/a000166

• Atlantic salmon
• alpha-tocopherol
• vitamin E
• lipid peroxidation
• malondialdehyde
• antioxidant enzymes
• fatty acids
• eicosapentaenoic acid
• docosahexaenoic acid

In this study the effect of increasing dietary alpha tocopherol on vitamin E tissue concentrations, lipid peroxidation (malondialdehyde), antioxidant enzymes, and fatty acid composition has been investigated in farmed Atlantic salmon. To this end fish (initial body weight similar to 193 g, n=70 per group) were fed diets based on fish oil (27.5 %), fish meal (15.0%), wheat gluten (20.6 %), and soy protein concentrate (24.0%) for 14 weeks. Diets were supplemented with 0 (negative control), 150, and 400 mg/kg vitamin E as all-rac alpha-tocopheryl acetate. Dietary vitamin E did not affect feed conversion efficiency ratio but significantly (p%26lt;0.05) increased alpha-tocopherol concentrations in salmon plasma, liver, and fillet (n=8 per group each). The increase in fillet alpha-tocopherol was accompanied by a considerable decrease (p%26lt;0.01) in malondialdehyde concentrations at the higher supplementation level. Furthermore, we observed an antagonistic interaction between alpha- and gamma-tocopherol in plasma at the highest supplementation level, since high dietary alpha-tocopherol reduced plasma gamma-tocopherol concentrations. Liver antioxidant enzymes, including glutathione peroxidase and superoxide dismutase, remained largely unchanged in response to dietary alpha-tocopherol. Dietary alpha-tocopherol did not affect eicosapentaenoic acid and docosahexaenoic acid concentrations in salmon fillet. Present data suggest that alpha-tocopherol supplementations beyond dietary recommendations may further improve flesh quality and nutritional value of Atlantic salmon fillet as far as malondialdehyde and vitamin E concentrations are concerned.

• 出版日期2013-8