科研之友
微信
新浪微博
Facebook
分享链接
摘要
An efficient procedure for the synthesis of 7-(aryl)-8-nitro-2,3,6,7-tetrahydroimidazo[1,2-a]pyridinones, 8-(aryl)-9-nitro-3,4,7,8-tetrahydropyridone[1,2-a]pyrimidines and 9-(aryl)-10-nitro-2,3,4,5,8,9-hexahydropyridone[1,2-a]diazepine via one-pot three component reaction of diamine, nitroketene dithioacetal (1,1-bis(methylsulfanyl)-2-nitroethene), and coumarine-3- carboxylic acid derivatives in EtOH under reflux conditions is reported. The advantages of this procedure are simplicity, easy purification, good yields, and catalyst-free conditions. All products were confirmed by H-1- and C-13-NMR, IR, MS, and X-ray crystal structure analyses.
- 出版日期2017-9
- 单位浙江大学
