Acute myeloid leukemia risk by industry and occupation

作者：Tsai Rebecca J^*; Luckhaupt Sara E; Schumacher Pam; Cress Rosemary D; Deapen Dennis M; Calvert Geoffrey M

来源：Leukemia and Lymphoma, 2014, 55(11): 2584-2591.

DOI：10.3109/10428194.2014.894189

• Acute myeloid leukemia
• industry
• occupation
• risk factors

Acute myeloid leukemia (AML) is the most common type of leukemia found in adults. Identifying jobs that pose a risk for AML may be useful for identifying new risk factors. A matched case-control analysis was conducted using California Cancer Registry data from 1988 to 2007. This study included 8999 cases of AML and 24 822 controls. Industries with a statistically significant increased AML risk were construction (matched odds ratio [mOR] = 1.13); crop production (mOR = 1.41); support activities for agriculture and forestry (mOR = 2.05); and animal slaughtering and processing (mOR = 2.09). Among occupations with a statistically significant increased AML risk were miscellaneous agricultural workers (mOR = 1.76); fishers and related fishing workers (mOR = 2.02); nursing, psychiatric and home health aides (mOR = 1.65); and janitors and building cleaners (mOR = 1.54). Further investigation is needed to confirm study findings and to identify specific exposures responsible for the increased risks.

• 出版日期2014-11
• 单位UC Davis