摘要

An efficient methodology for highly diastereoselective synthesis of poly-substituted 4,5-dihydropyrrole derivatives from readily available common reactants in water has been developed. During domino processes, the formation of pyrrole skeleton and its C2-hydroxylation and C3-arylamination were readily achieved via metal-free [3+2] heterocyclization in a one-pot operation.

  • 出版日期2013-8

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