摘要
An efficient methodology for highly diastereoselective synthesis of poly-substituted 4,5-dihydropyrrole derivatives from readily available common reactants in water has been developed. During domino processes, the formation of pyrrole skeleton and its C2-hydroxylation and C3-arylamination were readily achieved via metal-free [3+2] heterocyclization in a one-pot operation.
- 出版日期2013-8