A 6-year prospective surveillance of healthcare-associated infections in a neonatal intensive care unit from southern part of Turkey

作者：Yapicioglu Hacer^*; Satar Mehmet; Ozcan Kenan; Narli Nejat; Ozlu Ferda; Sertdemir Yasar; Tasova Yesim

来源：Journal of Paediatrics and Child Health, 2010, 46(6): 337-342.

DOI：10.1111/j.1440-1754.2010.01718.x

• Healthcare-associated infections
• neonatal intensive care unit
• surveillance
• predominant microorganisms

Aim:
To report the incidence of healthcare-associated infections (HAIs), site of infection and bacterial epidemiology in the Neonatal Intensive Care Unit in a university hospital in Adana, Turkey, between 2001 and 2006.
Methods:
During these years, HAIs were collected by an active surveillance system.
Results:
Five hundred one of 2832 infants hospitalised more than 72 h had 1124 HAI. The HAI incidence and incidence density ranged between 14.1 and 29.7 infections/100 patients, and 10.9-17.3 infections/1000 patient days within the study period; 61.5% of HAIs were ventilator-associated infections; 26.2% were bloodstream infections; 3.5% were urinary tract infections; 3.5% were necrotising enterocolitis (Stages II and III) and 1.4% was meningitis. The most frequent pathogens were gram-negative pathogens (75.6% of all infections) followed by gram-positive micro-organisms (21.4%) and Candida species (3.0%). Birthweight, gestational age and Apgar scores were lower and overall mortality rate (32.9% vs. 19.7%) and number of inpatient days were higher in patients with HAIs (for all P < 0.001) when compared with those who did not have HAIs. Furthermore, HAI rate was inversely related to birthweight (P < 0.001).
Conclusion:
In this study, the overall infection rate is high compared with developed countries and predominant micro-organisms are gram-negative enteric rods. These results strongly suggest the need for improving measures for prevention and control of HAIs in this hospital.

• 出版日期2010-6