Detection of Infectivity in Blood of Persons with Variant and Sporadic Creutzfeldt-Jakob Disease

作者:Douet Jean Yves; Zafar Saima; Perret Liaudet Armand; Lacroux Caroline; Lugan Severine; Aron Naima; Cassard Herve; Ponto Claudia; Corbiere Fabien; Torres Juan Maria; Zerr Inga; Andreoletti Olivier*
来源:Emerging Infectious Diseases, 2014, 20(1): 114-117.
DOI:10.3201/eid2001.130353

摘要

We report the presence of infectivity in erythrocytes, leukocytes, and plasma of 1 person with variant Creutzfeldt-Jakob disease and in the plasma of 2 in 4 persons whose tests were positive for sporadic Creutzfeldt-Jakob disease. The measured infectivity levels were comparable to those reported in various animals with transmissible spongiform encephalopathies.

  • 出版日期2014-1