摘要
A simple and efficient fluorescent chemosensor for Al3+ is reported in the paper. The chemosensor is obtained by dehydration reaction of 2-hydroxy-1-naphthaldehyde and 2-aminophenol. The chemosensor has high selectivity and sensitivity for Al3+ and displays fluorescence "off-on" switch signal. The detection limit of the chemosensor for Al3+ can reach 1.0 x 10(-7) M in DMSO/H2O (1:9, v/v) solution. The mass spectra and Job's plot analysis confirm the 1:1 stoichiometry between chemosensor and Al3+. Potential utilization of the probe as an intracellular sensor of Al3+ in human cancer (HiSa) cells is also examined by confocal fluorescence microscopy.