A closer look at strategies for preserving salivary gland function after radiotherapy in the head and neck region

作者：Galvao Moreira Leonardo Victor; Santana Thalita; Fontoura Nogueira da Cruz Maria Carmen

来源：Oral Oncology, 2016, 60: 137-141.

DOI：10.1016/j.oraloncology.2016.07.009

• Head and neck cancer
• Radiotherapy
• Radiation effects
• Salivary glands
• Salivation
• Xerostomia
• Cell
• and tissue-based therapy
• Drug therapy
• Radiation protection
• Regeneration

Radiation-induced damage to the salivary glands remains a major complication of using radiation therapy to treat head and neck cancer, and it has led a wide range of research attempting to resolve the problem. From this perspective, we sought to briefly discuss relevant and timely approaches aimed at protecting or regenerating irradiated salivary glands, thereby preventing the development of salivary hypofunction or rescuing the functional properties of damaged glands. Such findings include molecular, cell, tissue, organ, and drug-based therapies.

• 出版日期2016-9