Direct and mediated effects of cognitive function with multidimensional outcome measures in schizophrenia: The role of functional capacity

作者:Ho Jennifer S; Moore Raeanne C; Davine Taylor; Cardenas Veronica; Bowie Christopher R; Patterson Thomas L; Mau**ach Brent T*
来源:Journal of Clinical and Experimental Neuropsychology, 2013, 35(8): 882-895.
DOI:10.1080/13803395.2013.828021

摘要

Although cognitive ability is a known predictor of real-world functioning in schizophrenia, there has been an expanded interest in understanding the mechanisms by which it explains real-world functioning in this population. We examined the extent to which functional capacity (i.e., skills necessary to live independently) mediated the relationship between cognitive ability and both observer and self-reported real-world functioning in 138 outpatients with schizophrenia. Functional capacity significantly mediated the relations between cognitive ability and observer-rated real-world functioning, but not self-reported real-world functioning, with small to medium effect sizes observed for all outcomes. The role of cognitive ability in observer versus self-reported real-world functioning may be explained by different mechanisms.

  • 出版日期2013-10-1