科研之友
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摘要
During the screening of Nepalese ethnomedicinal plants for antiviral activities, Astilbe rivularis BUCH.-HAM., Saxifragaceae, was identified as a promising species. Bioassay-guided fractionation led to the isolation of arbutin, bergenin and a bergenin derivative. The structures were established by NMR studies. Except bergenin, the two compounds were found in this plant for the first time. A dimer of bergenin has not been described as a natural product before. The compounds showed in vitro antiviral activity against herpes simplex virus type-1 in non cytotoxic concentrations.
- 出版日期2011
- 单位河北医科大学
