Antineoplastic agents. 536. New sources of naturally occurring cancer cell growth inhibitors from marine organisms, terrestrial plants, and microorganisms

作者:Pettit George R*; Hogan Fiona; Xu Jun Ping; Tan Rui; Nogawa Toshihiko; Cichacz Zbigniew; Pettit Robin K; Du Jiang; Ye Qing Hua; Cragg Gordon M; Herald Cherry L; Hoard Michael S; Goswami Animesh; Searcy Justin; Tackett Larry; Doubek Dennis L; Williams Lee; Hooper John N A; Schmidt Jean M; Chapuis Jean Charles; Tackett Denise N; Craciunescu Felicia
来源:Journal of Natural Products, 2008, 71(3): 438-444.
DOI:10.1021/np700738k

摘要

Bioassay-guided fractionation of extracts of various plants, marine organisms, and microorganisms has led to the discovery of new natural sources of a number of known compounds that have significant biological activity. The isolation of interesting and valuable cancer cell growth inhibitors including majusculamide C (1), axinastatin 5 (5), bergazoles A (6), B (7), and E (8), manzamine A (10), jaspamide (11), and neoechinulin A (19) has been summarized.

  • 出版日期2008-3