A Toolkit of Engineered Recombinational Balancers in C. elegans

作者：Schwartz Hillel T; Sternberg Paul W^*

来源：Trends in Genetics, 2018, 34(4): 253-255.

DOI：10.1016/j.tig.2018.01.009

Dejima and colleagues report using CRISPR/Cas9 to generate a new collection of greatly improved balancer chromosomes in the standard laboratory nematode Caenorhabditis elegans, using methods previously reported by the same laboratory, expanding the set of C. elegans balancers to cover nearly 90% of coding genes.

• 出版日期2018-4