Associations of visceral fat area and physical activity levels with the risk of metabolic syndrome in postmenopausal women

作者:Zajac Gawlak Izabela; Klapcinska Barbara*; Kroemeke Aleksandra; Pospiech Dariusz; Pelclova Jana; Pridalova Miroslava
来源:Biogerontology, 2017, 18(3): 357-366.
DOI:10.1007/s10522-017-9693-9

摘要

This study was aimed at the evaluation of relationship between visceral fat area (VFA) and physical activity (PA) with the metabolic syndrome (MetS) risk in the physically active postmenopausal women. A total of 85 attendants of the University of the Third Age (U3A) aged 62.8 +/- 5.9 years (median time since menopause 11.8 y), participated in this study. VFA was assessed by bioimpedance method using InBody 720 analyzer. PA was assessed using the ActiGraph GT1 M accelerometer. Fasting levels of serum lipids (TG, HDL), serum glucose, waist circumference (WC) and blood pressure were measured to diagnose MetS according to NCEP-ATP III criteria. In 73 out of 85 participants the VFA exceeded the upper normal level of 100 cm(2), however, in almost a half of this group (n = 36) with elevated VFA (139.5 +/- 26.1 cm(2) on average), only 2 out of 5 criteria for MetS diagnosis were met. Participants were physically active, making on average 10,919 +/- 3435 steps/day. The risk of MetS occurrence in women with VFA > 100 cm(2) was twelve times higher (OR 12.33; CI 95% [1.5; 99.8]) than in the group with VFA < 100 cm(2). The participants from the group with the highest PA level (>12,500 steps/day) were at almost 4 times lower risk for MetS, than their less active counterparts (OR 3.84; CI 95% [1.27;11.64]). Increased level of VFA is a strong risk factor for the MetS in postmenopausal women, however high level of regular PA above the threshold of 12,500 steps/day may substantially reduce it.

  • 出版日期2017-6