A novel method for the synthesis of 3,5-disubstituted-(NH)-1,2,4-triazoles from 3,6-diaryl-1,2,4,5-tetrazines

作者：Haddadin Makhluf J^*; Zadeh Ebrahim H Ghazvini

来源：Tetrahedron Letters, 2010, 51(13): 1654-1656.

DOI：10.1016/j.tetlet.2010.01.061

The reaction of 3,6-diaryl-1,2,4,5-tetrazines and 2-aryl substituted acetonitriles, under basic conditions, leads unexpectedly to 3,5-diaryl-(NH)-1,2,4-triazoles in moderate yields. A mechanism is proposed.

• 出版日期2010-3-31