Anti-inflammatory effects of low-dose radiotherapy Indications, dose, and radiobiological mechanisms involved

作者：Arenas M^*; Sabater S; Hernandez V; Rovirosa A; Lara P C; Biete A; Panes J

来源：Strahlentherapie und Onkologie, 2012, 188(11): 975-981.

DOI：10.1007/s00066-012-0170-8

• Low-dose radiotherapy
• Leukocyte
• Endothelium
• Adhesion molecules
• Benign diseases

Low-dose radiotherapy (LD-RT) has been used for several benign diseases, including arthrodegenerative and inflammatory pathologies. Despite its effectiveness in clinical practice, little is known about the mechanisms through which LD-RT modulates the various phases of the inflammatory response and about the optimal dose fractionation. The objective of this review is to deepen knowledge about the most effective LD-RT treatment schedule and radiobiological mechanisms underlying the anti-inflammatory effects of LD-RT in various in vitro experiments, in vivo studies, and clinical studies.

• 出版日期2012-11