A disposable single-use electrochemical sensor for the detection of uric acid in human whole blood

作者：Chen JC; Chung HH; Hsu CT; Tsai DM; Kumar AS; Zen JM^*

来源：Sensors and Actuators B: Chemical , 2005, 110(2): 364-369.

DOI：10.1016/j.snb.2005.02.026

• screen-printed electrode
• single-use electrochemical sensors
• uric acid
• whole blood
• electrochemical test strip

We report here a non-enzymatic detecting electrode strip for fast monitoring of uric acid in human whole blood. A single-use amperometric uric acid sensor strip, incorporating a three-electrode configuration, has been fabricated on a polypropylene substrate using low cost screen-printing (thick-film) technology. Both the working and counter electrodes were prepared by screen-printing commercial carbon ink. The integration on the same support of pseudo-reference electrode was obtained by screen-printing a commercial silver ink and subsequent electrochemical pretreatment. Simply by placing a 20 mu l human whole blood drop on the strip is enough for uric acid analysis by square-wave voltammetry. Real human whole blood samples were analyzed by this method and compared to the phosphotungstic acid clinical test procedure with satisfactory results.

• 出版日期2005-10-14