科研之友
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摘要
A new derivative of triterpene named Erigeronol 1 was isolated from the EtOH extract of the aerial part of Conyza canadensis together with 15 known compounds for the first time from this plant. The structure of Erigeronol I was elucidated as 3-O-(hydroxyacetyl)-23,28-dihydroxy-beta-amyrin by hydrolysis and spectroscopic analysis. Erigeronol I showed potent cytotoxic activity with IC(50) value of 7.77 +/- 0.47 mu g/mL against melanoma B16 determined by the 3-(4,5-dimethylthiazo-2-yl)-2,5-diphenyltetrazolium bromide (MU) method.
