A Direct Palladium-Catalyzed Route to Selectively Substituted Carbazoles through Sequential C-C and C-N Bond Formation: Synthesis of Carbazomycin A

作者：Della Ca Nicola; Sassi Giovanni; Catellani Marta^*

来源：Advanced Synthesis & Catalysis, 2008, 350(14-15): 2179-2182.

DOI：10.1002/adsc.200800421

• carbazoles
• catalysis
• C-H activation
• norbornene
• palladium

The present paper offers a synthetically simple one-pot procedure for the catalytic preparation of the biologically interesting class of carbazoles. The new procedure is based on the combined catalysis of palladium and norbornene starting from o-substituted iodoarenes and N-sulfonylated or N-acetylated o-bromoanilines. A well-known member of this class, carbazomycin A, has been successfully prepared.

• 出版日期2008-10