Acute encephalopathy associated with the use of intravenous immunoglobulin. Report of one case

作者：Soto Alvaro V; Cartier R Luis

来源：Revista Medica de Chile, 2011, 139(10): 1340-1343.

• Guillain-Barre syndrome
• Immunoglobulin intravenous
• Neurotoxicity syndromes

Adverse reactions to intravenous immunoglobulin (ivIg) therapy, such as anaphylaxis, acute encephalopathy, aseptic meningitis, or thrombotic phenomena are uncommon. We report a 58-year-old man with hypertension presenting with muscle weakness which led to paraparesia and respiratory failure. With the diagnosis of Guillain-Barre syndrome (CBS), he was treated with ivIg. He developed an acute encephalopathy few hours after the administration of ivIg, with a decreased level of consciousness and agitation. A CT scan revealed moderate and diffuse brain edema. Encephalopathy resolved 96 hours after ivIg withdrawal and use of plasma exchange. A CT scan performed seven days after showed the resolution of brain edema. (Rev Med Chile 2011; 139: 1340-1343).

• 出版日期2011-10