Application of Reduced-FOV Diffusion-Weighted Imaging in Evaluation of Normal Pituitary Glands and Pituitary Macroadenomas

作者：Wang, M.; Liu, H.; Wei, X.; Liu, C.; Liang, T.; Zhang, X.; Jin, C.; Li, X.; Sun, Q.; Jiang, H.; Yang, J.^*

来源：American Journal of Neuroradiology, 2018, 39(8): 1499-1504.

DOI：10.3174/ajnr.A5735

• TURBO FIELD ECHO
• SPINAL-CORD
• COEFFICIENT
• MRI
• ADENOMA
• LESIONS
• HEAD
• NECK
• DWI

BACKGROUND AND PURPOSE:FOV optimized and constrained undistorted single-shot imaging provides relatively high-resolution images with few artifacts. This study evaluated the image quality and value of FOV optimized and constrained undistorted single-shot DWI in the evaluation of normal pituitary glands and pituitary macroadenomas. MATERIALS AND METHODS:Subjects with normal pituitary glands and patients with pituitary macroadenomas underwent FOV optimized and constrained undistorted single-shot and EPI DWI. Two neuroradiologists graded the image quality based on visualization of the pituitary stalk, pituitary gland, and pituitary macroadenoma. Intra- and interobserver agreements were assessed by statistics. Image quality and ADCs were compared between the 2 methods by the paired Wilcoxon signed rank test and t test. Differences in ADC between normal pituitary glands and macroadenomas were analyzed by the independent-samples t test. RESULTS:Twenty-eight subjects with normal pituitary glands and 16 patients with macroadenomas were enrolled. Intra- and interobserver agreements for image-quality assessment were moderate to substantial. Relative to EPI DWI, FOV optimized and constrained undistorted single-shot DWI exhibited obviously better image quality both in normal pituitary glands and macroadenomas. There was no significant difference in ADCs of macroadenomas between the 2 methods. Macroadenomas with soft consistency (0.75 0.14 x 10(-3) mm(2)/s) had significantly lower mean ADC than normal pituitary glands (1.18 +/- 0.19 x 10(-3) mm(2)/s; P < .001). CONCLUSIONS:FOV optimized and constrained undistorted single-shot DWI helps acquire high-resolution images of normal pituitary glands and pituitary macroadenomas with relatively few susceptibility artifacts in a clinically feasible scan time. This sequence might be helpful for evaluating the consistency of pituitary macroadenomas.

• 出版日期2018-8
• 单位西安交通大学